Since the antiplatelet agent aspirin is associated with a reduce risk of death and distant metastasis in cancer patients [25–27] including those with ovarian cancer [28], we investigated the effect of aspirin and the antiplatelet P2Y12 blocker, 2-methylthioadenosine 5′-monophosphate triethylammonium salt hydrate (2MeSAMP), on the platelet cancer cell interaction. This evidence concerns the gene P2RY12 and ovarian cancer.