HAS1 and dysplasia: HAS-1 percentage in basal cellhyperplasia was 63.14 ± 20.18 whereas average HAS-1-positive cell percentages in otherpre-neoplastic lesions were squamous metaplasia: 64.84 ± 16.60; moderate dysplasia:66.32 ± 13.96; atypical adenomatous hyperplasia: 46.63 ± 31.81; and severe dysplasia:51.61 ± 22.54 (P<0.05).