We sequenced the MYD88 gene (OMIM: 602170) using HaloPlex targeted capture on an Illumina MiSeq, in 41 cases with IgM monoclonal component (27 WM, 14 IgM MGUS), 5 additional family members with IgG monoclonal component or full-blown multiple myeloma (4 IgG-MGUS, 1 IgA-myeloma), and 2 healthy individuals, from 20 unrelated families with at least two cases of WM or IgM MGUS (S1 Table and S1 Fig). This evidence concerns the gene CD79A and plasma cell myeloma.