KLK4 and coronary artery disorder: In 2013, Yao et al31 evaluated whetherthe levels of both tissue kallikrein and the inflammatory biomarker high-sensitivityC-reactive protein (hs-CRP) in the peripheral blood would correlate with plaquestability, as well as the relationship among tissue kallikrein expression, macrophagenumbers, and angiogenesis in CAD.