The largest autozygous interval, which encompasses a genomic region of 47 Mb (hg: 72-118.9 Mb) contains CDHR1. Several additional genes known to be involved in inherited retinal dystrophies were also within these intervals, namely LRAT underlying Leber Congenital Amaurosis (LCA)30 and AILP1 underlying LCA, juvenile RP and autosomal dominant CRD31, 32. The gene discussed is LRAT; the disease is Leber congenital amaurosis.