MMP-8 levels were also significantly elevated in the periodontitis group (314.1 ± 25.5 ng/mL) compared to both gingivitis (199.0 ± 29.1) and healthy (130.7 ± 14.5) subjects, although there appeared to be a greater overlap across the groups with this analytes vs. the others that were examined. This evidence concerns the gene MMP8 and periodontitis.