Eosinophilia in lung tissue is driven partially by the recruitment of eosinophils to the lung mucosa and interstitium due to airway produced IL-5, as well as production of eotaxin (CCL11), eotaxin-2 (CCL24), and eotaxin-3 (CCL26) [58, 59]. This evidence concerns the gene CCL26 and Increased total eosinophil count.