Due to activation of STAT3 and the over-induction of antiapoptotic genes found on cervical cancer cell lines after PRL stimulation, we decided to inhibit the STAT3 activation using the inhibitor AG490; which resulted in an impaired induction of Bcl-xl, Bcl-2, survivin and Mcl-1. The gene discussed is BIRC5; the disease is cervical carcinoma.