Interestingly, Nfil3−/−, but not CD1d−/−, BM lost the ability to rescue Fah−/− mice from liver failure since Nfil3−/− BMT markedly decreased Fah−/− mouse survival and Fah+ BMDH generation after NTBC withdrawal (Fig. 2d,e). The gene discussed is NFIL3; the disease is liver failure.