The blood group reactive lectin Griffonia simplicifolia (GS-I), which recognizes alpha-galactosyl moieties is recognized as a surrogate marker to identify tumor expressed antigens reactive with anti-Gal antibodies [70], and GS-I lectin is of utility to interrogate terminal α-GalNAc/Gal expression on human tissues [71]. The gene discussed is GAL; the disease is neoplasm.