Also, the results reported in this study suggest that repeated peak flow measurements in patients with COPD provide a helpful tool able to identify adverse environmental impacts; these measurements should include spirometry and potentially more sensitive markers for inflammation pathways in areas such as exhaled Nitric oxide (NO), Interleukin (Il)-8, or another inflammatory cytokine [47,48,49,50]. The gene discussed is CXCL8; the disease is chronic obstructive pulmonary disease.