iASPP is overexpressed in diverse human tumors, including colorectal cancer [53], acute leukemia [54], endometrioid endometrial cancer [55], lung cancer [56], glioblastoma [57], head and neck squamous cell carcinoma [58], prostate cancer [59], hepatocellular carcinoma [60, 61, 62], oral squamous cell carcinoma [63, 64], cervical cancer [65] and ovarian cancer [66]. Here, PPP1R13L is linked to Familial prostate cancer.