Further, to support the novel role of NF-ĸB and STAT3 as potential therapeutic targets in prevention and treatment of IBD, Fitzpatrick [18] reported that Vidofludimus, an antibody drug, could inhibit IL-17 secretions in activated splenocytes by inhibiting STAT3 and NF-ĸB signaling pathways. The gene discussed is STAT3; the disease is inflammatory bowel disease.