CD4 and tuberculosis: A significantly higher frequency of these CD4+ T cells was found in active TB patients (median 1.197%, range 0.219%–3.59%) and in LTBI patients (1.666%, 0.234–5.762%) if compared to healthy controls (0.246%, 0–0.423%; P < 0.0001 by Kruskal-Wallis test); on the other hand, no significant differences were found between the 2 infected group subjects.