The most well-characterized mutation loci for early-onset autosomal recessive PD are PARK2(Parkin) , PINK1, and PARK7, ATP13A2 whereas those for the autosomal dominant form of PD are SCNA and LRRK2. The susceptible genes associated with PD are Tau, Nurr1 and GBA. The gene discussed is LRRK2; the disease is Parkinson disease.