Additionally, dysregulated genes related to RIG-I-like receptor signaling (Day et al., 2005; Katsuno et al., 2011; Zhu et al., 2014), tryptophan metabolism (Sandyk, 2006), ErbB signaling (Gorlewicz et al., 2009), and cell cycle (Manzano et al., 2013) have been reported in ALS (Gorlewicz et al., 2009; Manzano et al., 2013). The gene discussed is EGFR; the disease is amyotrophic lateral sclerosis.