Although mice with embryonic deletion of Stat5 in all tissues have severe perinatal lethality, Vav1-Cre/+Stat5abfl/fl mice showed normal survival but with the diagnostic signs of Stat5 deficiency including anemia and lymphopenia (Supplementary Figure S1A–S1C; Supplementary Table S1). The gene discussed is VAV1; the disease is anemia (phenotype).