From these genes 25 were already included as disease-associated genes in DisGeNET version 2.1 (from 5th of May 2014) used in our analysis above, and 15 of them were associated to diseases with known involvement of monocytes or cell types derived from them (e.g. arthritis, pycnodysostosis, myeloid leukemia and properdin deficiency). The gene discussed is CFP; the disease is arthritic joint disease.