GPT and Decreased total leukocyte count: With regard to hematological toxicities, including laboratory disorders, frequently encountered toxicities were grade 3 or 4 neutropenia, leukopenia, thrombocytopenia, anemia, and elevation of AST and ALT, which were recorded in 5 (10.6 %), 2 (4.3 %), 2 (4.3 %), 3 (6.4 %), 11 (23.4 %), and 10 (21.3 %) of the 47 patients, respectively.