ALB and neoplasm: Predisposing factors besides dosimetry, such as the tumor type (infiltrative or not), tumor volume (>70 %), elevated basal transaminases (≥5 N), elevated basal bilirubin (≥2 mg/dL or 34mmmol/L) or a combination of tumor volume ≥50 % with albumin level <30 G/L, [55] have already been described as having an impact on toxicity.