Plasma leptin (0.83  ±  0.41 vs. 0.79  ±  0.42, p = 0.610), SDNN (2.00  ±  0.13 vs. 2.04  ±  0.14, p = 0.165), and SDANN5 (1.96  ±  0.13 vs. 1.99  ±  0.14, p = 0.183) were not significantly different when compared between diabetic patients with (n = 48) and without (n = 52) neuropathy. Here, LEP is linked to neuropathy.