In total, 14 reports of EGFR mutation status concordance between matched primary and metastatic tumours were identified, of which four were in Caucasian patients: Kalikaki et al. [46] (Table 3) analysed 25 primary tumours and corresponding lung (n = 9), thoracic wall (n = 5), adrenal gland (n = 4), brain (n = 3), bone (n = 2), skin (n = 1) and liver (n = 1) metastases, and determined the EGFR mutation status concordance to be 72 % (18/25). Here, EGFR is linked to metastatic neoplasm.