EGFR and metastatic neoplasm: In a US study, Munfus-McCray et al. [48] (Table 3) assessed 9 primary tumours and corresponding metastatic tumours of the brain (n = 3), lymph node (n = 3) or pleura/knee/lung (n = 1 each), and found EGFR mutation status concordance to be 89 % (8/9).