To validate if pancreatic cancer derived exosomal miR-212-3p would inhibit RFXAP and MHC II of iDC, iDC were stimulated by SW1990 and BxPC-3 derived exosomes respectively (named as BxPC-3 exo-iDC and SW1990 exo-iDC respectively). The gene discussed is RFXAP; the disease is familial pancreatic carcinoma.