All patients with the shortest survival (within 1–3 months after tumor resection) had SFRP1 promoter methylated, whereas the frequency of SFRP1 methylation in patients who survived longer was lower (73 % and 83 % methylated tumor samples in the “3–12 months” and “12–24 months after tumor resection” groups, respectively). This evidence concerns the gene SFRP1 and neoplasm.