As depicted in Table 1 and Figure 1, two genes OLIG1 and BAG3 were highly up-regulated and eight genes PRDM16, GLDNA, APOA1, CCKBR, EDN3, VAV3, CXCR4, and GHRL were down regulated in pancreas with T2D as compared to pancreas control. This evidence concerns the gene PRDM16 and type 2 diabetes mellitus.