SOCS1 and diffuse large B-cell lymphoma: Although comparison to mutational rates at SHM consensus motifs in cHL (n = 16/166 = 9%) is significantly lower than that observed in DLBCL (n = 33/120; 27.5%; P < 0.01, Fisher's exact test) [20], our data suggest that SOCS1 mutations are at least in part caused by aberrant SHM.