Comparison by mutation subtype showed that cHL patients with HRS-cells that harbor SOCS1 minor mutations had different time courses of FFDP when compared to the SOCS1 major subgroup (P = 0.05; Figure 3e); however, overall survival of SOCS1 minor patients was similar to SOCS1 wild-type patients (P = 0.88; Figure 3f). This evidence concerns the gene SOCS1 and classic Hodgkin lymphoma.