Eighty-one breast cancer patients were recruited: 3 were excluded because they missed follow-up (1 triple-negative breast cancer (TNBC) and 2 HER2-positive) and 3 HER2-positive patients underwent NAC only (including 1 luminal with HER[3+]) and 2 HER2-positive). The gene discussed is ERBB2; the disease is breast carcinoma.