Although phosphorylation of VASP at S157 has been suggested as a marker for the potential of metastatic progression of prostate cancer [12], using this phosphorylation as a marker needs to be pursued with caution, since additional phosphorylations at S239/T278 or S322 can diverge the functions of VASP at the leading edge of migrating cells [8]. The gene discussed is VASP; the disease is Familial prostate cancer.