In the univariate analyses, female sex, non-Chinese ethnicity age and timing of cART initiation and, both baseline CD4+ T-cell count (P = .001 and log-transformed HIV-1 RNA viral load (P = .257) and absence of co-infections (P = .050) were significantly associated with the rate of CD4+ T-cell recovery to ≥350 cells/μL. This evidence concerns the gene CD4 and coinfection.