This gene was firstly identified in 2003 from early-stage non-small cell lung cancer (NSCLC) cells with highly expression level [1], subsequently a number of publications reported that Malat1 is also as one of the major genes that highly up regulates in different cancers including endometrial cancer [2], breast cancer [3]; cervical cancer [4]; colorectal cancer [5]; hepatocellular carcinoma [6]; liver cancer [7]; neuroblastoma [8]; osteosarcoma [9], pancreatic cancer [10], prostate cancer [11], bladder cancer [12], and gastric cancer [13]. The gene discussed is MALAT1; the disease is non-small cell lung carcinoma.