Emerging evidence has indicated significant associations of single nucleotide polymorphisms (SNPs) in FCRL3 gene with several autoimmune diseases, including rheumatoid arthritis (RA), thyroid disease,21 systemic lupus erythematosus,22 and Graves’ disease.23 Moreover, it is proposed that the same susceptibility loci may lead to diverse autoimmune diseases.24 Hence, there might be an association between FCRL3 gene and endometriosis, which has gradually attracted increasing attention. Here, FCRL3 is linked to systemic lupus erythematosus.