OATP1B1-dependent transport could well be important for the acid (active) form of simvastatin, (and other statins less hydrophobic than pravastatin) as SLCO1B1 variants were recently associated with simvastatin-induced myopathies [9], implying that OATP1B1 was involved with simvastatin transport. This evidence concerns the gene SLCO1B1 and myopathy.