IL5 and inflammation: For instance, neutrophilic airway inflammation was associated with poor corticosteroid responses31 and corticosteroid treatment guided by eosinophilic inflammation led to better disease outcome than standard clinical management.32, 33 Interestingly, patient selection guided by sputum eosinophils also appears to be a better predictor of a patient's responses to anti–IL-5 antibody treatment.34, 35, 36