Furthermore, we found significant differences (p<0.01) in the CSF levels of IFN-γ (385.21±16.34 pg/ml) in the ALS≥12 m subgroup compared with the serum levels of IFN-γ either in the ALS≥12 m subgroup (289.34±17.48 pg/ml) or in the ALS<12 m subgroup (262.82±30.91 pg/ml). Here, IFNG is linked to amyotrophic lateral sclerosis.