IFNG and amyotrophic lateral sclerosis: As shown in Fig 3A, the CSF IFN-γ levels was markedly increased in the ALS<12 m (273.92±24.50 pg/ml) and ALS≥12 m (385.21±16.34 pg/ml) subgroups compared with the non-ALS patients (172.22±17.61 pg/ml, P<0.01).