These properties limit the toxicity of all antimicrobials whereas OMP mutations that further reduce OM permeability have been found in antibiotic-resistant cells.[2] Understanding the structure and function of the OM is therefore vital for human health[3] but it is challenging because bacterial cells are very small and the creation of accurate model systems is technically challenging.[4] As a result, although we have a clear knowledge of the chemical composition of the OM, our understanding of its physical and dynamic properties lags far behind our knowledge of other biological membranes.[5]. This evidence concerns the gene OMP and ocular melanoma.