At the second MRS assessment (Table 4), patients with MSA-C still had lower NAA/Cr, Cho/Cr in the cerebellar hemispheres and vermis than those with SCA3 and lower NAA/Cr in the cerebellar hemispheres than those with SCA2 and SCA6. The gene discussed is CACNA1A; the disease is multiple system atrophy, cerebellar type.