However, proof of envisioned efficacy is still lacking (Dr. James Voelker of Eli Lilly and Co. reported at the ASN Kidney Week 2014 that anti-TGFβ1 therapy in patients with advanced diabetic nephropathy with a humanized anti-TGFβ1 antibody LY2382770 in a phase II dose-ranging study was terminated early due to efficacy futility [22]). This evidence concerns the gene TGFB1 and diabetic kidney disease.