In addition, in HIV mono-infected individuals presenting neuropathy, there was a higher, but not statistically significant, frequency of the inflammatory marker CD49d in Treg cells (median and IQR = 63 and 21.1 %) compared to the control group (median and IQR = 51,8; 20.7 %, p = 0.167). The gene discussed is ITGA4; the disease is neuropathy.