Downregulation of AXL using MP470 (Amuvatinib) reversed EMT in mesenchymal normal human mammary epithelial cells and in a clinical study, Amuvatinib was well tolerated and showed antitumor activity when combined with paclitaxel/carboplatin and carboplatin/etoposide in neuroendocrine, NSCLC, and SCLC tumors [47]. Here, AXL is linked to non-small cell lung carcinoma.