In both mixed cultures (C4-2 tumor cells plus WPMY-1 myofibroblasts (Figure 7a), and C4-2 tumor cells plus THP-1 TAM-like cells (Figure 7b)), enzalutamide induced CCL2 and etanercept blocked CCL2 induction, consistent with our proposed paracrine mechanism. This evidence concerns the gene CCL2 and neoplasm.