POU5F1 and hepatocellular carcinoma: IGF2BP3 overexpression deregulated ABCB1, ABCG2 and CD133 mRNA expression in Huh7, MHCC-97L and PLC/PRF/5 cells (Figure 4B), and we observed a moderate upregulation of the expression of the stemness-related genes Nanog and Oct-4 in HCC cells (Supplementary Figure S3).