Differently, latency type II, which is characterized by the expression of LMP1 and 2, occurs in patients with Hodgkin's lymphomas and T/NK lymphomas, while latency-III, which encompasses expression of all the main EBV proteins are expressed, including EBNA1–2-3, and LMP1–2, is associated with immunodeficiency/immunosuppression states like HIV infection or organ transplantation, or with in vitro culturing of latency I cells, like some BL cell lines [10]. This evidence concerns the gene PDLIM7 and immunodeficiency disease.