BCL2 and neoplasm: However, when we extended the sequence analysis to the DH-JH region and to the tumor specific t(14;18) rearrangement we identified 21 insertions in the FL1 N1 and N2 regions of CDR3 as compared to FL2 R9129, and an identical BCL2/IgH rearrangement, carrying a mutation in the 3’ of BCL2 in the FL1 R8403 (S6A Fig).