[29, 30] The detection of an increased number of CD10 positive cells in both the PGC and ME compartments from FL samples, as compared to tonsils and t-FL (S1D Fig) is consistent with the detection of tumor clones within all our sorted populations and fits with the recent mouse models describing B memory cells being able to circulate and disseminate not only in peripheral blood but also in lymphoid organs.[31]. This evidence concerns the gene MME and neoplasm.