The normalized expression level of the 17-kDa TMEM88 isoform in breast cancer tissues (mean ± SD:1.019 ± 0.697) was significantly higher than that in the paired noncancerous tissues (mean ± SD:0.579 ± 0.408; p = 0.011; Figure 1G and 1H). Here, TMEM88 is linked to breast cancer.