Interestingly, chicken Igf2bp1 with the non-phosphorylatable Y396F mutation is transported to axons similarly to wild-type Igf2bp1 but it decreases growth cone turning towards netrin in mouse cortical neurons and also decreases neurite outgrowth in primary hippocampal neurons and neuroblastoma cells [4,12,13]. The gene discussed is IGF2BP1; the disease is neuroblastoma.