Thus, we next examined c-Met, Bcl2 and cyclin D1 expression in human primary lung tumors (NSCLS) and pair-matched lung tissues, and our western blot results demonstrated that the expression of c-Met, Bcl2 and cyclin D1 proteins were all increased in lung cancer tissues compared with normal lung tissues (Fig. 2A, 2C and 2E). This evidence concerns the gene BCL2 and lung cancer.