The c-Rel GEP signature in the WT-p53 subcohort included oncogene JUN, CTTN which contributes to tumor cell invasion and metastasis, ENG involved in the regulation of angiogenesis, SH3GL1 with a role in cell cycle whose overexpression may play a role in leukemogenesis, LPIN1 and CKMT1A/B involved in metabolism regulation, and many genes involved in Golgi function. The gene discussed is ENG; the disease is neoplasm.