Our coimmunoprecipitation analysis using nuclear extracts purified from representative human derived GCB- and ABC-DLBCL cell lines (MS, DB, LR, LP) however showed that c-Rel predominantly binds to p65 in all cell lines (more intense in GCB than ABC cell lines); and that in some cell lines, p52 and RelB also formed dimers with c-Rel but to a lesser extent (Fig. 1I). The gene discussed is RELA; the disease is diffuse large B-cell lymphoma.