REL and diffuse large B-cell lymphoma: On the other hand, the differential expression of these DEGs between c-Rel+ and c-Rel− within the p65+ or p50+ ABC-DLBCL groups also suggested that c-Rel/NF-κB dimers compared with other p65 or p50 dimers have significantly distinct roles in regulation of proliferation, apoptosis, metabolism, trafficking, cell adhesion, migration, and angiogenesis.