Given its strong enrichment in Müller cells and described alterations of Müller cell functions in diabetic retina that are partially because of diabetes-induced oxidative stress (80, –82), investigations on the functional role of Prdx6 in normal Müller cells and, importantly, in Müller cells of the diabetic retina would be of highest interest to elucidate whether altered expression levels are associated with the development of diabetic retinopathy. The gene discussed is PRDX6; the disease is diabetic retinopathy.