These isomers increased the expression of Interleukin (IL)-24 mRNA which is associated with anti-tumour effects and decreased the levels of the pro-angiogenic cytokines, IL-6 and IL-8 in murine mammary cancer cells (4T1) and human umbilical vein endothelial cells (HUVEC)22, 23. The gene discussed is IL24; the disease is breast cancer.