While various studies on miRNAs have compared miRNA deregulation between normal and tumoral pituitary tissues (Data S1 in Supplementary Material) thus highlighting miRNA involvement in pituitary tumorigenesis, to our knowledge, only one other study has investigated miRNA in tumoral progression by comparing the differences between adenomas and carcinomas in ACTH pituitary tumors (21). Here, POMC is linked to pituitary tumor.