Correlations between the expression of transcription factors and miRNA were calculated using Spearman test and only ETS2:miR183 (r = 0.43, p = 0.0167) showed significant correlation in the pituitary tumors studied, moreover, ETS2 showed a significant down-regulation at the mRNA level in the aggressive tumors compared to the non-aggressive ones (Figure 5A; Table S4 in Supplementary Material). This evidence concerns the gene ETS2 and pituitary tumor.